P32890 protein in UniLectin3D

Fold

Class

Family

Origin

Species

Available structures

1DJR : aGal-carboxyphenil 1EEF : aGal 1EFI : aGal-nitrophenyl 1LTA : aGal 1LTB : no ligand 1LTS : no ligand 1LTT : bGal14Glc 2XRQ : bGal13bGalNAc14(aNeuAc23)bGal1 2XRS : bGal14bGlcNAc13bGal14Glc 5LZI : Inhibitor MM146 6IAL : no ligand

Related proteins
> 50% identity

ProtVista PDB viewer

Reference of
6IAL structure
2019
PubMed

Heggelund J, Heim J, Bajc G, Hodnik V, Anderluh G, Krengel U.
Specificity of Escherichia coli Heat-Labile Enterotoxin Investigated by Single-Site Mutagenesis and Crystallography. International journal of molecular sciences 2019

Reference of
5LZI structure
2017
PubMed

Heggelund J, Mackenzie A, Martinsen T, Heim J, Cheshev P, Bernardi A, Krengel U.
Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics. Scientific reports 2017

Reference of
2XRQ structure
2011
PubMed

Holmner A, Mackenzie A, Okvist M, Jansson L, Lebens M, Teneberg S, Krengel U.
Crystal structures exploring the origins of the broader specificity of escherichia coli heat-labile enterotoxin compared to cholera toxin. J. Mol. Biol. 2011

Reference of
2XRS structure
2011
PubMed

Reference of
1EEF structure
2001
PubMed

Fan E, Merritt E, Zhang Z, Pickens J, Roach C, Ahn M, Hol W.
Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta crystallographica. Section D, Biological crystallography 2001

Reference of
1EFI structure
2001
PubMed

Reference of
1DJR structure
2000
PubMed

Minke W, Pickens J, Merritt E, Fan E, Verlinde C, Hol W.
Structure of m-carboxyphenyl-alpha-D-galactopyranoside complexed to heat-labile enterotoxin at 1.3 A resolution: surprising variations in ligand-binding modes. Acta crystallographica. Section D, Biological crystallography 2000

Reference of
1LTA structure
1994
PubMed

Merritt, E.A., Sixma, T.K., Pronk, S.E., Kalk, K.H., Van Zanten, B.A.M., Hol, W.G.J.
Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT) Mol. Microbiol. 1994

Reference of
1LTB structure
1994
PubMed

Merritt, E.A., Pronk, S.E., Sixma, T.K., Kalk, K.H., Van Zanten, B.A.M., Hol, W.G.J.
Structure of partially-activated E. coli heat-labile enterotoxin (LT) at 2.6 A resolution FEBS Letters 1994

Reference of
1LTS structure
1993
PubMed

Sixma, T.K., Van Zanten, B.A.M., Dauter, Z., Hol, W.G.J.
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin J. Mol. Biol. 1993

Reference of
1LTT structure
1992
PubMed

Sixma, T.K., Pronk, S.E., Kalk, K.H., Van Zanten, B.A.M., Berghuis, A.M., Hol, W.G.J.
Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography Nature 1992

How to cite

How to cite: