Q9HYN5 protein in UniLectin3D

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Class

Family

Origin

Species

Available structures

1GZT : aLFuc 1OUR : Man 1OUS : no ligand 1OUX : no ligand 1OVP : fructose 1OVS : Man 1OXC : Fuc 1UZV : aLFuc 1W8F : bGal14bGlcNAc13bGal14(aFuc13)G 1W8H : bGal13(aFuc14)GlcNAc 2BOJ : b-D-AraOMe 2BP6 : a-L-GalOMe 2JDH : aFuc(1-4)GlcNAc disaccharide d 2JDK : aFuc(1-4)GlcNAc disaccharide d 2JDM : aLFucOMe 2JDN : aManOMe 2JDP : aLFucOMe 2JDU : aLFucOMe 2JDY : aManOMe 2VUC : synthetic fucose derivative 2VUD : synthetic fucose derivative 3DCQ : Synthetic fucopeptide 3ZDV : Synthetic mannose derivative 4CE8 : aFuc 5A3O : Synthetic mannose derivative 5D2A : Synthetic fucopeptide 5HCH : aFuc 5NES : Fuc 5NEY : Fuc 5NF0 : Fuc 6Q6W : C-fucosylated D-antimicrobial 6Q6X : C-fucosylated D-antimicrobial 6Q77 : C-fucosylated D-antimicrobial 6Q79 : C-fucosylated D-antimicrobial 6Q85 : C-fucosylated D-antimicrobial 6Q86 : C-fucosylated D-antimicrobial 6Q87 : C-fucosylated D-antimicrobial 6Q8D : C-fucosylated D-antimicrobial 6Q8G : C-fucosylated D-antimicrobial 6Q8H : C-fucosylated D-antimicrobial 6R35 : bGal14(aFuc13)bGlcNAc13Gal 8AIJ : Fucose derivative 8AIY : Fucose derivative

Related proteins
> 50% identity

ProtVista PDB viewer

Reference of
8AIJ structure
2022
PubMed

Mala P, Siebs E, Meiers J, Rox K, Varrot A, Imberty A, Titz A.
Discovery of N-beta-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB. Journal of medicinal chemistry 2022

Reference of
8AIY structure
2022
PubMed

Mala P, Siebs E, Meiers J, Rox K, Varrot A, Imberty A, Titz A.
Discovery of N-beta-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecB. Journal of medicinal chemistry 2022

Reference of
6R35 structure
2019
PubMed

Lepsik M, Sommer R, Kuhaudomlarp S, Lelimousin M, Paci E, Varrot A, Titz A, Imberty A.
Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study. European journal of medicinal chemistry 2019

Reference of
6Q86 structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q79 structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q6W structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q6X structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q8G structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q8H structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q87 structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q85 structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q77 structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
6Q8D structure
2019
PubMed

Baeriswyl S, Gan B, Siriwardena T, Visini R, Robadey M, Javor S, Stocker A, Darbre T, Reymond J.
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 2019

Reference of
5NF0 structure
2017
PubMed

He R, Di Bonaventura I, Visini R, Gan B, Fu Y, Probst D, Lüscher A, Köhler T, van Delden C, Stocker A, Hong W, Darbre T, Reymond J.
Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical science 2017

Reference of
5NES structure
2017
PubMed

He R, Di Bonaventura I, Visini R, Gan B, Fu Y, Probst D, Lüscher A, Köhler T, van Delden C, Stocker A, Hong W, Darbre T, Reymond J.
Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical science 2017

Reference of
5NEY structure
2017
PubMed

He R, Di Bonaventura I, Visini R, Gan B, Fu Y, Probst D, Lüscher A, Köhler T, van Delden C, Stocker A, Hong W, Darbre T, Reymond J.
Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical science 2017

Reference of
5D2A structure
2016
PubMed

Michaud, G., Visini, R., Bergmann, M., Salerno, G., Bosco, R., Gillon, E., Richichi, B., Nativi, C., Imberty, A., Stocker, A., Darbre, T., Reymond, J.-L.
Overcoming antibiotic resistance in Pseudomonas aeruginosa biofilms using glycopeptide dendrimers Chem. Sci. 2016

Reference of
5HCH structure
2016
PubMed

Roethlisberger, P., Istrate, A., Marcaida Lopez, M.J., Visini, R., Stocker, A., Reymond, J.L., Leumann, C.J.
X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair Chem. Commun. 2016

Reference of
5A3O structure
2015
PubMed

Sommer, R., Hauck, D., Varrot, A., Wagner, S., Audfray, A., Prestel, A., Moleer, H.M., Imberty, A., Titz, A.
Cinnamide Derivatives of D-Mannose as Inhibitors of the Bacterial Virulence Factor Lecb from Pseudomonas Aeruginosa ChemistryOpen 2015

Reference of
3ZDV structure
2013
PubMed

Hauck D, Joachim I, Frommeyer B, Varrot A, Philipp B, Möller H, Imberty A, Exner T, Titz A.
Discovery of two classes of potent glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes. ACS chemical biology 2013

Reference of
3DCQ structure
2008
PubMed

Johansson E, Crusz S, Kolomiets E, Buts L, Kadam R, Cacciarini M, Bartels K, Diggle S, Cámara M, Williams P, Loris R, Nativi C, Rosenau F, Jaeger K, Darbre T, Reymond J.
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chemistry & biology 2008

Reference of
2JDH structure
2007
PubMed

Marotte K, Sabin C, Preville C, Moume-Pymbock M, Wimmerova M, Mitchell EP, Imberty A, Roy R.
X-ray dtructures and thermodynamics of the interaction of PA-IIL from Pseudomonas aeruginosa with disaccharide derivatives ChemMedChem 2007

Reference of
2JDK structure
2007
PubMed

Marotte K, Sabin C, Preville C, Moume-Pymbock M, Wimmerova M, Mitchell EP, Imberty A, Roy R.
X-ray dtructures and thermodynamics of the interaction of PA-IIL from Pseudomonas aeruginosa with disaccharide derivatives ChemMedChem 2007

Reference of
2JDM structure
2007
PubMed

Adam J, Pokorna M, Sabin C, Mitchell EP, Imberty A, Wimmerova M.
Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference. BMC Struct. Biol. 2007

Reference of
2JDN structure
2007
PubMed

Adam J, Pokorna M, Sabin C, Mitchell EP, Imberty A, Wimmerova M.
Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference. BMC Struct. Biol. 2007

Reference of
2JDP structure
2007
PubMed

Adam J, Pokorna M, Sabin C, Mitchell EP, Imberty A, Wimmerova M.
Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference. BMC Struct. Biol. 2007

Reference of
2JDU structure
2007
PubMed

Adam J, Pokorna M, Sabin C, Mitchell EP, Imberty A, Wimmerova M.
Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference. BMC Struct. Biol. 2007

Reference of
2JDY structure
2007
PubMed

Adam J, Pokorna M, Sabin C, Mitchell EP, Imberty A, Wimmerova M.
Engineering of PA-IIL lectin from Pseudomonas aeruginosa - Unravelling the role of the specificity loop for sugar preference. BMC Struct. Biol. 2007

Reference of
2BOJ structure
2006
PubMed

Sabin C, Mitchell EP, Pokorna M, Gautier C, Utille JP, Wimmerova M, Imberty A.
Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: thermodynamics data correlated with X-ray structures FEBS Lett. 2006

Reference of
2BP6 structure
2006
PubMed

Sabin C, Mitchell EP, Pokorna M, Gautier C, Utille JP, Wimmerova M, Imberty A.
Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: thermodynamics data correlated with X-ray structures FEBS Lett. 2006

Reference of
1UZV structure
2005
PubMed

Mitchell EP, Sabin C, Snajdrova L, Pokorna M, Perret S, Gautier C, Hofr C, Gilboa-Garber N, Koca J, Wimmerova M, Imberty A
High affinity fucose binding of Pseudomonas aeruginosa lectin PA-IIL: 1.0 A resolution crystal structure of the complex combined with thermodynamics and computational chemistry approaches Proteins Struct. Funct. Genet. 2005

Reference of
1W8F structure
2005
PubMed

Perret S, Sabin C, Dumon C, Pokorná M, Gautier C, Galanina O, Ilia S, Bovin N, Nicaise M, Desmadril M, Gilboa-Garber N, Wimmerová M, Mitchell E, Imberty A.
Structural basis for the interaction between human milk oligosaccharides and the bacterial lectin PA-IIL of Pseudomonas aeruginosa. The Biochemical journal 2005

Reference of
1W8H structure
2005
PubMed

Perret S, Sabin C, Dumon C, Pokorná M, Gautier C, Galanina O, Ilia S, Bovin N, Nicaise M, Desmadril M, Gilboa-Garber N, Wimmerová M, Mitchell E, Imberty A.
Structural basis for the interaction between human milk oligosaccharides and the bacterial lectin PA-IIL of Pseudomonas aeruginosa. The Biochemical journal 2005

Reference of
1OUR structure
2003
PubMed

Loris R, Tielker D, Jaeger KE, Wyns L
Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa J. Mol. Biol. 2003

Reference of
1OUS structure
2003
PubMed

Loris R, Tielker D, Jaeger KE, Wyns L
Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa J. Mol. Biol. 2003

Reference of
1OUX structure
2003
PubMed

Loris R, Tielker D, Jaeger KE, Wyns L
Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa J. Mol. Biol. 2003

Reference of
1OVP structure
2003
PubMed

Loris R, Tielker D, Jaeger KE, Wyns L
Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa J. Mol. Biol. 2003

Reference of
1OVS structure
2003
PubMed

Loris R, Tielker D, Jaeger KE, Wyns L
Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa J. Mol. Biol. 2003

Reference of
1OXC structure
2003
PubMed

Loris R, Tielker D, Jaeger KE, Wyns L
Structural basis of carbohydrate recognition by the lectin LecB from Pseudomonas aeruginosa J. Mol. Biol. 2003

Reference of
1GZT structure
2002
PubMed

Mitchell E, Houles C, Sudakevitz D, Wimmerova M, Gautier C, Perez S, Wu AM, Gilboa-Garber N, Imberty A
Structural basis for oligosaccharide-mediated adhesion of Pseudomonas aeruginosa in the lungs of cystic fibrosis patients Nature Struct. Biol. 2002

Reference of
2VUC structure
0
PubMed

Beha, S., Marotte, K., Sabin, C., Mitchell, E.P., Imberty, A., Roy, R
Fucose-Derived Glycomimetics as High Affinity Ligands for Bacterial Lectin Pa-Iil from Pseudomonas Aeruginosa to be published 0

Reference of
2VUD structure
0
PubMed

Beha, S., Marotte, K., Sabin, C., Mitchell, E.P., Imberty, A., Roy, R
Fucose-Derived Glycomimetics as High Affinity Ligands for Bacterial Lectin Pa-Iil from Pseudomonas Aeruginosa to be published 0

Reference of
4CE8 structure

PubMed

Beha, S., Marotte, K., Sabin, C., Mitchell, E.P., Imberty, A., Roy, R
Fucose-Derived Glycomimetics as High Affinity Ligands for Bacterial Lectin Pa-Iil from Pseudomonas Aeruginosa to be published 0