SMTL ID : 2jhk.1

Structure of globular heads of M-ficolin complexed with N-acetyl-D- glucosamine

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.75 Å

Oligo State

monomer

Ligands

1 x CA: CALCIUM ION(Non-covalent)

CA.1: 4 residues within 4Å: Chain A: D.154, D.156, S.158, S.160 5 PLIP interactions: 4 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:D.154, A:D.156, A:S.158, A:S.160, H2O.5

1 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)

NAG.2: 6 residues within 4Å: Chain A: F.166, D.174, C.175, H.176, A.193, Y.204 8 PLIP interactions: 8 interactions with chain A Hydrophobic interactions: A:F.166, A:A.193, A:Y.204 Hydrogen bonds: A:C.175, A:H.176, A:Y.204, A:Y.204, A:Y.204

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Garlatti, V. et al., Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem. (2007)

Release Date

2007-10-09

Peptides

FICOLIN-1: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
F

FICOLIN-1

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