SMTL ID : 4cou.1

Crystal Structure of Epithelial Adhesin 6 A domain (Epa6A) from Candida glabrata in complex with Lactose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.48 Å

Oligo State

monomer

Ligands

1 x BGC- GAL: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose(Non-covalent)

BGC-GAL.1: 11 residues within 4Å: Chain A: C.74, W.75, C.115, D.160, D.161, W.194, R.222, D.223, N.224, D.225 Ligands: CA.2 7 PLIP interactions: 7 interactions with chain A Hydrogen bonds: A:W.75, A:N.224, A:D.160, A:R.222, A:R.222, A:D.223, A:D.223, A:N.224, A:D.225 Water bridges: A:C.74, A:R.222

1 x CA: CALCIUM ION(Non-covalent)

CA.2: 6 residues within 4Å: Chain A: D.160, D.161, N.221, D.223, D.225 Ligands: BGC-GAL.1 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:D.160, A:D.161, A:D.223, A:D.225

1 x ACT: ACETATE ION(Non-functional Binders)

ACT.3: 5 residues within 4Å: Chain A: S.63, Y.64, D.65, H.92, R.93 6 PLIP interactions: 6 interactions with chain A Hydrophobic interactions: A:D.65 Hydrogen bonds: A:S.63, A:D.65 Water bridges: A:R.93 Salt bridges: A:H.92, A:R.93

1 x GOL: GLYCEROL(Non-functional Binders)

GOL.4: 5 residues within 4Å: Chain A: Y.66, S.69, C.115, T.116, S.117 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:S.69, A:S.117 Water bridges: A:K.68, A:S.69, A:G.70

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Diderrich, R. et al., Structural Hotspots Determine Functional Diversity of the Candida Glabrata Epithelial Adhesin Family. J.Biol.Chem. (2015)

Release Date

2015-02-18

Peptides

EPITHELIAL ADHESIN 6: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

EPITHELIAL ADHESIN 6

Related Entries With Identical Sequence