5lzh.1 | SWISS-MODEL Template Library

SMTL ID : 5lzh.1

Cholera toxin classical B-pentamer in complex with inhibitor PC262

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 1.13 Å
Oligo State
homo-pentamer
Ligands
5 x 7BN: (2~{R},4~{S},5~{R},6~{R})-5-acetamido-2-[4-[3-[2-[(2~{S},3~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]ethylamino]-3-oxidanylidene-propyl]-1,2,3-triazol-1-yl]-4-oxidanyl-6-[(1~{R},2~{R})-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid(Non-covalent)
1 x MRD: (4R)-2-METHYLPENTANE-2,4-DIOL(Non-functional Binders)
3 x CA: CALCIUM ION(Non-covalent)
1 x TRS: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL(Non-functional Binders)
1 x PEG: DI(HYDROXYETHYL)ETHER(Non-functional Binders)
Links
RCSB   PDBe   PDBj   PDBsum   CATH   PLIP
Citation
Heggelund, J.E. et al., Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics. Sci Rep (2017)
Release Date
2017-05-31
Peptides
Cholera enterotoxin B subunit: ABCDE
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
A
B
B
C
C
D
D
E
E

Cholera enterotoxin B subunit

Toggle Identical (ABCDE)

Related Entries With Identical Sequence

1eei.1 | 1fgb.1 | 1jr0.1 | 1jr0.2 | 1llr.1 | 1md2.1 | 1pzj.1 | 1pzk.1 | 1rcv.1 | 1rd9.1 | 1rdp.1 | 1rf2.1 | 1s5b.1 | 1s5c.1 | 1s5d.1 | 1s5e.1 | 1s5e.2 | 1s5f.1 | 1s5f.2 | 5elb.1 | 5elb.2 | 5eld.1 | 6hjd.1 | 6hjd.2 | 6hmw.1 | 6hmw.2 | 6hmy.1 | 6hmy.2