- Coordinates
- PDB Format
- Method
- X-RAY DIFFRACTION 2.23 Å
- Oligo State
- homo-heptamer
- Ligands
- 3 x MAN- MAN- MAN- MAN- MAN- MAN: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose
- 1 x MAN: alpha-D-mannopyranose(Non-covalent)
- 15 x EDO: 1,2-ETHANEDIOL(Non-functional Binders)
EDO.5: 7 residues within 4Å:- Chain C: K.30, E.64, I.66
- Chain F: E.8, V.9, G.10, Y.82
4 PLIP interactions:2 interactions with chain C, 2 interactions with chain F- Hydrogen bonds: C:K.30, C:K.30, F:G.10, F:G.10
EDO.6: 6 residues within 4Å:- Chain C: E.8, V.9, G.10, Y.82
- Chain D: K.30, E.64
4 PLIP interactions:2 interactions with chain C, 2 interactions with chain D- Hydrogen bonds: C:G.10, C:G.10, D:K.30, D:K.30
EDO.7: 5 residues within 4Å:- Chain D: Y.37, K.60, S.129, D.130
- Ligands: MAN-MAN-MAN-MAN-MAN-MAN.1
2 PLIP interactions:2 interactions with chain D- Hydrogen bonds: D:K.60, D:S.129
EDO.8: 7 residues within 4Å:- Chain D: E.8, P.16, F.17, T.18, K.124, G.125, R.133
3 PLIP interactions:3 interactions with chain D- Hydrogen bonds: D:T.18, D:R.133, D:R.133
EDO.9: 2 residues within 4Å:- Chain D: M.104, F.108
No protein-ligand interaction detected (PLIP)EDO.10: 2 residues within 4Å:- Chain D: G.77, T.96
No protein-ligand interaction detected (PLIP)EDO.11: 2 residues within 4Å:- Chain D: Q.21, E.22
1 PLIP interactions:1 interactions with chain D- Hydrogen bonds: D:E.22
EDO.12: 7 residues within 4Å:- Chain D: V.9, G.10, Y.82, K.84, G.85
- Chain E: K.30, E.64
5 PLIP interactions:3 interactions with chain D, 2 interactions with chain E- Hydrogen bonds: D:G.10, D:G.10, D:G.85, E:K.30, E:K.30
EDO.13: 4 residues within 4Å:- Chain E: R.89, S.129, D.130
- Ligands: MAN-MAN-MAN-MAN-MAN-MAN.2
1 PLIP interactions:1 interactions with chain E- Hydrogen bonds: E:R.89
EDO.14: 6 residues within 4Å:- Chain A: K.30, E.64
- Chain E: E.8, V.9, G.10, Y.82
2 PLIP interactions:1 interactions with chain A, 1 interactions with chain E- Hydrogen bonds: A:K.30, E:G.10
EDO.15: 4 residues within 4Å:- Chain F: G.77, S.78, V.79, T.96
1 PLIP interactions:1 interactions with chain F- Hydrogen bonds: F:G.77
EDO.16: 6 residues within 4Å:- Chain F: K.30, E.64
- Chain G: V.9, G.10, Y.82
- Ligands: EDO.19
4 PLIP interactions:2 interactions with chain F, 2 interactions with chain G- Hydrogen bonds: F:K.30, F:K.30, G:G.10, G:G.10
EDO.17: 5 residues within 4Å:- Chain B: V.9, G.10, Y.82
- Chain G: K.30, E.64
3 PLIP interactions:1 interactions with chain B, 2 interactions with chain G- Hydrogen bonds: B:G.10, G:K.30, G:E.64
EDO.18: 6 residues within 4Å:- Chain G: Y.37, K.60, R.89, S.129, D.130
- Ligands: MAN-MAN-MAN-MAN-MAN-MAN.3
5 PLIP interactions:5 interactions with chain G- Hydrogen bonds: G:K.60, G:K.60, G:R.89, G:R.89, G:S.129
EDO.19: 4 residues within 4Å:- Chain F: S.28, E.44
- Chain G: T.7
- Ligands: EDO.16
2 PLIP interactions:2 interactions with chain F- Hydrogen bonds: F:S.28, F:S.28
- Links
- RCSB PDBe PDBe-KB PDBj PDBsum CATH PLIP
- Citation
- Sivaji, N. et al., Mevo lectin specificity towards high-mannose structures with terminal alpha Man(1,2) alpha Man residues and its implication to inhibition of the entry of Mycobacterium tuberculosis into macrophages. Glycobiology (2021)
- Release Date
- 2021-04-21
- Peptides
- lectin: ABCDEFG
- SMTL:PDB
- SMTL Chain Id:
PDB Chain Id:A
DB
EC
AD
BE
CF
GG
F
- Coordinates
- PDB Format
- Method
- X-RAY DIFFRACTION 2.23 Å
- Oligo State
- homo-heptamer
- Ligands
- 3 x MAN- MAN- MAN- MAN- MAN- MAN: alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose
- 1 x MAN: alpha-D-mannopyranose(Non-covalent)
- 15 x EDO: 1,2-ETHANEDIOL(Non-functional Binders)
- Links
- RCSB PDBe PDBe-KB PDBj PDBsum CATH PLIP
- Citation
- Sivaji, N. et al., Mevo lectin specificity towards high-mannose structures with terminal alpha Man(1,2) alpha Man residues and its implication to inhibition of the entry of Mycobacterium tuberculosis into macrophages. Glycobiology (2021)
- Release Date
- 2021-04-21
- Peptides
- lectin: ABCDEFG
- SMTL:PDB
- SMTL Chain Id:
PDB Chain Id:A
DB
EC
AD
BE
CF
GG
F