SMTL ID : 7qpu.1 (1 other biounit)

Botulinum neurotoxin A5 cell binding domain in complex with GM1b oligosaccharide

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.40 Å

Oligo State

monomer

Ligands

1 x GAL- SIA: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose(Non-covalent)

GAL-SIA.1: 9 residues within 4Å: Chain A: Y.254, E.340, F.389, H.390, S.401, W.403, Y.404, F.415, G.416 6 PLIP interactions: 6 interactions with chain A Hydrogen bonds: A:E.340, A:H.390, A:S.401, A:S.401, A:Y.254, A:Y.254, A:Y.404, A:G.416 Salt bridges: A:H.390 Hydrophobic interactions: A:Y.254, A:F.389

Links

RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP

Citation

Gregory, K.S. et al., Crystal Structures of Botulinum Neurotoxin Subtypes A4 and A5 Cell Binding Domains in Complex with Receptor Ganglioside. Toxins (2022)

Release Date

2022-03-09

Peptides

Botulinum neurotoxin sub-type A5: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

Botulinum neurotoxin sub-type A5

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