7qui.1 | SWISS-MODEL Template Library

SMTL ID : 7qui.1

Crystal structure of the N-terminal domain of Siglec-8 in complex with sulfonamide sialoside analogue

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 3.35 Å
Oligo State
homo-dimer
Ligands
2 x F9I: (2~{S},4~{S},5~{R},6~{R})-5-acetamido-2-[(2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-acetamido-2-(hydroxymethyl)-4,6-bis(oxidanyl)oxan-3-yl]oxy-3,5-bis(oxidanyl)-6-(sulfooxymethyl)oxan-4-yl]oxy-6-[(1~{R},2~{R})-3-(naphthalen-2-ylsulfonylamino)-1,2-bis(oxidanyl)propyl]-4-oxidanyl-oxane-2-carboxylic acid(Non-covalent)
Links
RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP
Citation
Lenza, M.P. et al., Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody. Jacs Au (2023)
Release Date
2023-01-18
Peptides
Sialic acid-binding Ig-like lectin 8: AB
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
B
B
A

Sialic acid-binding Ig-like lectin 8

Related Entries With Identical Sequence

7qu6.1 | 7qu6.2 | 7qu6.3 | 7qu6.4 | 7qu6.5 | 7qu6.6