7z63.1 | SWISS-MODEL Template Library

SMTL ID : 7z63.1

Structure of the LecA lectin from Pseudomonas aeruginosa in complex with a biaryl-thiogalactoside

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 1.75 Å
Oligo State
homo-tetramer
Ligands
4 x CA: CALCIUM ION(Non-covalent)
4 x IE3: [3-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-4-methoxy-phenyl]-(3,4,5-trimethoxyphenyl)methanone(Non-covalent)
1 x EDO: 1,2-ETHANEDIOL(Non-functional Binders)
Links
RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP
Citation
Bruneau, A. et al., Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. Eur.J.Med.Chem. (2022)
Release Date
2023-01-18
Peptides
PA-I galactophilic lectin: ABCD
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
AAA
B
BBB
C
CCC
D
DDD