SMTL ID : 4oit.1 (1 other biounit)

Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.24 Å

Oligo State

homo-dimer

Ligands

4 x MAN: alpha-D-mannopyranose(Non-covalent)

MAN.1: 8 residues within 4Å: Chain A: Q.29, D.31, N.33, V.35, Y.37, A.42, S.45, N.49 6 PLIP interactions: 6 interactions with chain A Hydrogen bonds: A:Q.29, A:N.33, A:Y.37, A:Y.37, A:S.45, A:S.45 MAN.2: 6 residues within 4Å: Chain A: Q.59, D.61, N.63, Y.67 Chain B: P.72, K.79 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:Q.59, A:D.61, A:N.63, A:Y.67 MAN.3: 7 residues within 4Å: Chain A: Q.89, D.91, N.93, V.95, Y.97, P.102, S.105 8 PLIP interactions: 8 interactions with chain A Hydrogen bonds: A:Q.89, A:D.91, A:N.93, A:Y.97, A:Y.97, A:S.105 Water bridges: A:D.91, A:D.91 MAN.4: 5 residues within 4Å: Chain B: Q.89, D.91, N.93, Y.97, S.105 6 PLIP interactions: 6 interactions with chain B Hydrogen bonds: B:Q.89, B:D.91, B:N.93, B:Y.97, B:S.105, B:S.105

1 x BMA: beta-D-mannopyranose(Non-covalent)

BMA.5: 8 residues within 4Å: Chain A: P.72, H.75, K.79 Chain B: Q.59, D.61, N.63, V.65, Y.67 7 PLIP interactions: 5 interactions with chain B, 2 interactions with chain A Hydrogen bonds: B:Q.59, B:D.61, B:N.63, B:Y.67, B:Y.67, A:H.75 Salt bridges: A:H.75

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Patra, D. et al., Structure, interactions and evolutionary implications of a domain-swapped lectin dimer from Mycobacterium smegmatis. Glycobiology (2014)

Release Date

2014-07-23

Peptides

LysM domain protein: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

LysM domain protein

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