5f2f.1 | SWISS-MODEL Template Library

SMTL ID : 5f2f.1

Crystal structure of para-biphenyl-2-methyl-3', 5' di-methyl amide mannoside bound to FimH lectin domain

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 1.66 Å
Oligo State
monomer
Ligands
1 x 5U7: 5-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-methyl-phenyl]-~{N}1,~{N}3-dimethyl-benzene-1,3-dicarboxamide(Non-covalent)
2 x GOL: GLYCEROL(Non-functional Binders)
Links
RCSB   PDBe   PDBj   PDBsum   CATH   PLIP
Citation
Jarvis, C. et al., Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI. Chemmedchem (2016)
Release Date
2016-05-04
Peptides
Protein FimH: A
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
A