6qns.1 | SWISS-MODEL Template Library

SMTL ID : 6qns.1

Crystal structure of the binding domain of Botulinum Neurotoxin type B mutant I1248W/V1249W in complex with human synaptotagmin 1 and GD1a receptors

Coordinates
PDB Format
Method
X-RAY DIFFRACTION 2.40 Å
Oligo State
hetero-1-1-mer
Ligands
1 x BGC- GAL- NGA- GAL- SIA- SIA: N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose(Non-functional Binders)
Links
RCSB   PDBe   PDBj   PDBsum   CATH   PLIP
Citation
Yin, L. et al., Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. Plos Biol. (2020)
Release Date
2020-02-26
Peptides
Botulinum neurotoxin type B: A
Synaptotagmin-1: B
SMTL:PDB
SMTL Chain Id:
PDB Chain Id:
A
A
B
S

Botulinum neurotoxin type B

Synaptotagmin-1

Related Entries With Identical Sequence

4isq.1 | 4isq.2 | 4isq.3 | 6g5f.1 | 6g5k.1 | 6g5k.2 | 6zvn.1