2VU9 structure in UniLectin3D

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Comments

Botulinum neurotoxin serotype A1 complexed with GT1B

Stenmark P, Dupuy J, Imamura A, Kiso M, Stevens R. Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction. PLoS pathogens 2008

Matching protein

P0DPI0 in UniLectin

Available structures

2VU9 : aNeuAc23bGal13bGalNAc14(aNeuAc
2VUA : no ligand
5TPB : no ligand
5TPC : GD1-a pentasaccharide

Related proteins
> 50% identity

Ligand

Glycan composition

IUPAC condensed

GlycoCT

RES
1b:x-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:b-dgal-HEX-1:5
6s:n-acetyl
7b:b-dgal-HEX-1:5
8b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
9s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:2o(4+1)5d
5:5d(2+1)6n
6:5o(3+1)7d
7:7o(3+2)8d
8:8d(5+1)9n

PubMed DOI RCSB.ORG PDBeGlyTouCan (glycan information)SwissModel (ligand interactions)Glyconnect and SugarBind glycan superstructure(s)Uniprot Sugarbind lectin

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